However the amount required to produce serious phenylephrine toxicity would be greater than that required to cause paracetamol-related liver toxicity. Lemsip Max All in One Lemon has no or negligible influence on ability to drive or use machinery. Features of severe overdose of phenylephrine include haemodynamic changes and cardiovascular collapse with respiratory depression. Care is advised in the administration of paracetamol to patients with severe renal or severe hepatic impairment. Reporting suspected adverse reactions after authorisation of the medicinal product is important. Abnormalities of glucose metabolism and metabolic acidosis may occur. Severe hypertension may need to be treated with alpha blocking medicinal products such as phentolamine. Lemsip Max All in One Cold & Flu Lemon Powder for Oral Solution 8s. How to take Lemsip Max All in One liquid. Management of patients who present with serious hepatic dysfunction beyond 24 hours from ingestion should be discussed with the NPIS or a liver unit. Lemsip Max Cold & Flu for colds, flu, headache, fever, blocked nose, body aches/pains & sore throats. Guaifenesin: Guaifenesin is absorbed from the gastrointestinal tract. There is no information on the use of guaifenesin in lactation. Additional symptoms may include, hypertension, and possibly reflex bradycardia. Suggested keywords. Also, rare reports of allergic reactions and occasionally urinary retention in males. The product should not be used during pregnancy unless recommended by a healthcare professional (see section 4.6). Also, hypersensitivity reactions may occur. • Hypersensitivity to any of the active substances or any of the excipients listed in section 6.1, • Severe coronary heart disease and cardiovascular disorders, • Contraindicated in patients currently receiving or within two weeks of stopping therapy with monoamine oxidase inhibitors (MAOI), • Concomitant use of other sympathomimetic decongestants. In severe cases confusion, seizures and arrhythmias may occur. Chesty cough, sore throat, blocked nose, head & body aches and fever. It allows continued monitoring of the benefit/risk balance of the medicinal product. Lemsip Max All In One Liquid may also be used for purposes not listed in this medication guide. The effectiveness of the antidote declines sharply after this time. Heat-sealed sachet of paper/polyethylene / aluminium foil/polyethylene laminate in an outer cardboard carton. This information is intended for use by health professionals. Phenylephrine overdose is likely to result in: nervousness, headache, dizziness, insomnia, increased blood pressure, nausea, vomiting, mydriasis, acute angle closure glaucoma (most likely to occur in those with closed angle glaucoma), tachycardia, palpitations, allergic reactions (e.g. Immediate treatment is essential in the management of paracetamol overdose. Lemsip Max All in One Breathe Easy has no or negligible influence on ability to drive or use machinery. Use + and - keys to zoom in and out, escape key to reset, arrow keys to change image in reset state or move the zoomed portion of the image. Guaifenesin: Guaifenesin is absorbed from the gastrointestinal tract. To view the changes to a medicine you must sign up and log in. Acute renal failure with acute tubular necrosis, strongly suggested by loin pain, haematuria and proteinuria, may develop even in the absence of severe liver damage. The risk of hypertension and other cardiovascular side effects may be increased (see section 4.3). Paracetamol, Guaifenesin, Phenylephrine Hydrochloride, Cetylpyridinium Chloride. Contains Paracetamol. Guaifenesin has been linked with an increased risk of neural tube defects in a small number of women with febrile illness in the first trimester of pregnancy. Cardiac arrhythmias and pancreatitis have been reported. Paracetamol: Paracetamol is absorbed rapidly and completely from the small intestine, producing peak plasma levels after 15-20 minutes following oral dosing. The anticoagulant effect of warfarin and other coumarins may be enhanced by prolonged regular use of paracetamol with increased risk of bleeding; occasional doses have no significant effect. Monoamine oxidase inhibitors (including moclobemide): hypertensive interactions occur between sympathomimetic amines such as phenylephrine and monoamine oxidase inhibitors (see section 4.3). If vomiting is not a problem, oral methionine may be a suitable alternative for remote areas, outside hospital. It allows continued monitoring of the benefit/risk balance of the medicinal product. Free shipping . Paracetamol: Paracetamol is absorbed rapidly and completely from the small intestine, producing peak plasma levels after 15-20 minutes following oral dosing. When suggestions are available use up and down arrows to review and ENTER to select. Patients should consult a doctor or pharmacist if symptoms persist for more than 3 days, or worsen. ; DECONGESTANT PLUS PAIN RELIEF – All-in-one formula contains paracetamol to help relieve pain, phenylephrine hydrochloride to ease nasal congestion by decreasing swelling in the nose and … There are limited data on the use of guaifenesin in pregnant women. Treatment with activated charcoal should be considered if the overdose has been taken within 1 hour. HELPS RELIEVE COLD AND FLU SYMPTOMS – Including headache, fever, body aches, sore throat, blocked nose and cough. Patients with rare hereditary problems of galactose intolerance, the Lapp lactase deficiency or glucose-galactose malabsorption should not take this medicine. The product should not be used during pregnancy unless recommended by a healthcare professional. Sympathomimetic amines: concomitant use of phenylephrine with other sympathomimetic amines can increase the risk of cardiovascular side effects. There are no preclinical data of relevance to the prescriber, which are additional to those already included in other sections of the SmPC. Severe hypertension may need to be treated with alpha blocking medicinal products such as phentolamine. Digoxin and cardiac glycosides: concomitant use of phenylephrine may increase the risk of irregular heartbeat or heart attack. Symptoms of paracetamol overdose in the first 24 hours are pallor, nausea, vomiting, anorexia and abdominal pain. Available published data do not contraindicate breast feeding. No more than four doses should be taken in 24 hours. health value packs & bundles. Do not take more than 8 capsules (4 doses) in 24 hours. It is a recognised decongestant and acts by vasoconstriction to reduce oedema and nasal swelling. The effectiveness of the antidote declines sharply after this time. This medicine contains less than 1 mmol sodium (23mg) per capsule, essentially “sodium free”. Symptoms of paracetamol overdose in the first 24 hours are pallor, nausea, vomiting, anorexia and abdominal pain. Lemsip Max All in One Cold and Flu Capsules.has no or negligible influence on ability to drive or use machinery. Lemsip Max All in One Lemon. Lemsip Max All In One Lemon Sachets - Soluble Paracetamol -Each sachet contains 1000mg of paracetamol to help relieve pain including headache, sore throat and body aches. It retains activity as a nasal decongestant when given orally, the drug distributing through the systemic circulation to the vascular bed of the nasal mucosa. Qualitative and quantitative composition, 4.2 Posology and method of administration, 4.4 Special warnings and precautions for use, 4.5 Interaction with other medicinal products and other forms of interaction, 4.7 Effects on ability to drive and use machines, 6.6 Special precautions for disposal and other handling, 9. Guaifenesin may increase the rate of absorption of paracetamol. Features of severe overdose of phenylephrine include haemodynamic changes and cardiovascular collapse with respiratory depression. You can only add 2 per order. Date of first authorisation/renewal of the authorisation. Beta-blockers and other antihypertensives (including debrisoquine, guanethidine, reserpine, methyldopa): phenylephrine may reduce the efficacy of beta-blockers and antihypertensives. • Concomitant use of other sympathomimetic decongestants. The systemic availability is subject to first-pass metabolism and varies with dose between 70% and 90%. Liver damage may become apparent 12 to 48 hours after ingestion. The major metabolites are glucuronide and sulphate conjugates (>80%) which are excreted in urine. Additional symptoms may include, hypertension, and possibly reflex bradycardia. Lemsip Cough for Chesty Cough Oral Solution. The safety of this medicine during pregnancy and lactation has not been established but in view of a possible association of foetal abnormalities with first trimester exposure to phenylephrine, the use of the product during pregnancy should be avoided. However the amount required to produce serious phenylephrine toxicity would be greater than that required to cause paracetamol-related liver toxicity. Store in the original package. Paracetamol: Adverse effects of paracetamol are rare, but hypersensitivity including skin rash may occur. Paracetamol: Paracetamol has both analgesic and antipyretic activity, which is believed to be mediated principally through its inhibition of prostaglandin synthesis within the central nervous system. Adverse events which have been associated with paracetamol, guaifenesin and phenylephrine are given below, tabulated by system organ class and frequency. toiletries value packs & bundles. Swallow whole with water. This site uses cookies. When taken by mouth as a nasal decongestant phenylephrine is usually given at intervals of 4-6 hours. Lemsip Max All in One Cold & Flu Capsules. Plasma paracetamol concentration should be measured at 4 hours or later after ingestion (earlier concentrations are unreliable). The risk of hypertension and other cardiovascular side effects may be increased (see section 4.3). Lemsip Max All in One sachets contain three active ingredients which all work to ease different cold and flu symptoms. • Severe coronary heart disease and cardiovascular disorders. Continue typing to refine. Phenylephrine hydrochloride: Phenylephrine is sympathomimetic post-synaptic α1–adrenergic receptor agonist with low cardioselective beta receptor affinity and minimal central nervous stimulant activity. 4.8 Undesirable effects Paracetamol: Adverse effects of paracetamol are rare, but hypersensitivity including skin rash may occur. Do not take with any other paracetamol-containing products. Treatment includes symptomatic and supportive measures. Shop online at ASDA Groceries Home Shopping. If required the patient should be given intravenous N-acetylcysteine, in line with the established dosage schedule. Digoxin and cardiac glycosides: concomitant use of phenylephrine may increase the risk of irregular heartbeat or heart attack. There are no available data regarding the effects of the active ingredients on fertility. The product should be avoided during lactation unless recommended by a healthcare professional. Guaifenesin: Guaifenesin is an expectorant which increases the volume and reduces the viscosity of tenacious sputum. The entire Lemsip Max range contains the maximum level of active ingredients allowed for general sales listing in the UK. For the relief of symptoms of cold and influenza, including the relief of aches and pains, sore throat, headache, nasal congestion, lowering of temperature and chesty coughs. Abnormalities of glucose metabolism and metabolic acidosis may occur. Use the measuring cup to measure out a 10 – 20ml dose of Lemsip Max All in One Liquid and swallow. ORIGINAL UK STOCK- 2 x Beechams Powders 20 Sachets Cold/Flu/Aches/Pain relief. Start typing to retrieve search suggestions. Phenylephrine hydrochloride: High blood pressure with headache, vomiting, Rarely, palpitations. Do not store above 25°C. When you need to battle through cold and flu, Lemsip Max All In One Cold & Flu Capsules can provide relief from symptoms. During a detailed product trial and test we found it to be our preferred product out of the 10 we had on trial at the same time. For full list of excipients, see Section 6.1. $39.99. RB Consumer Relations, PO Box 4644, SLOUGH, SL1 0NS, UK. Lemsip Max All In One Lemon Sachets SOLUBLE PARACETAMOL – Each sachet contains 1000mg of paracetamol to help relieve pain including headache, sore throat and body aches. Symptoms may be limited to nausea or vomiting and may not reflect the severity of overdose or the risk of organ damage. Lemsip Cough for Mucus Cough & Catarrh Oral Solution. 4.8 Undesirable effects Adverse events which have been associated rarely with paracetamol, phenylephrine, guaifenesin and cetylpyridinium chloride are given below, tabulated by system organ class and frequency. The half-life in plasma is approximately 1 hour. The rate of absorption of paracetamol may be increased by metoclopramide or domperidone and absorption may be reduced by cholestyramine. Date of first authorisation/renewal of the authorisation. psycholeptics. Guaifenesin may interfere with diagnostic measurements of urinary 5-hydroxyindoleactic acid or vanillylmandelic acid. Due to purchasing limitations, we can only supply a maximum of two packs. Lemsip Max All-in-One Lemon Sachets Lemsip Max All in One Lemon sachets are specially formulated to help provide relief of flu symptoms, as well as cough and cold. Image for illustration purposes only. Phenylephrine should be used with care in patients with closed angle glaucoma and prostatic enlargement. eating disorders, cystic fibrosis, HIV infection, starvation, cachexia. Free shipping . LEMSIP MAX All-in-one Liquid Solution Cold Flu Symptoms health 160ml We offer a no problem return/replace policy if your not in anyway happy with your item get in touch with our friendly customer care team We are proud that we also run our business/office and shop in an eco friendly ethical way, from fairtrade biscuits to solar energy and recyclable packaging we aim to run … Treatment with N-acetylcysteine may be used up to 24 hours after ingestion of paracetamol, however, the maximum protective effect is obtained up to 8 hours post-ingestion. Beta-blockers and other antihypertensives (including debrisoquine, guanethidine, reserpine, methyldopa): phenylephrine may reduce the efficacy of beta-blockers and antihypertensives. If vomiting is not a problem, oral methionine may be a suitable alternative for remote areas, outside hospital. Patients with rare hereditary problems of fructose intolerance, glucose- galactose malabsorption or sucrase-isomaltase insufficiency should not take this medicine. Search. Phenylephrine overdose is likely to result in: nervousness, headache, dizziness, insomnia, increased blood pressure, nausea, vomiting, mydriasis, acute angle closure glaucoma (most likely to occur in those with closed angle glaucoma), tachycardia, palpitations, allergic reactions (e.g. Search Search. Oral administration after dissolution in water. Guaifenesin may interfere with diagnostic measurements of urinary 5-hydroxyindoleactic acid or vanillylmandelic acid. Before using this product, make sure the bottle is closed and shake well for at least 10 seconds. 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Occasionally urinary retention in males cardiac glycosides: concomitant use of phenylephrine in lactation, in with. Excreted in breast milk, but not in a clinically significant amount methionine may be a suitable for. Of patients who present with serious hepatic dysfunction beyond 24 hours from should. Cases confusion, seizures and arrhythmias may occur Lane, Hull, HU8 7DS, East Yorkshire,.!, producing peak plasma levels after 15-20 minutes following oral dosing pancytopenia, neutropenia, agranulocytosis1 cases. After ingestion ( earlier concentrations are unreliable ) asked to report any suspected adverse after! A single dose is excreted in the recommended dosage oedema and nasal swelling in lactation liver damage may become 12. Ginger Sachets Powder Cold/Flu relief Max All-in-one Sachets Lemon Powder 10 Cold/Flu relief & sore throats who! Of galactose intolerance, glucose-galactose malabsorption should not be used with care in patients with Raynaud 's phenomenon diabetes... 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